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CGRP: A new era for migraine treatment
Migraine is a common medical condition, affecting as many as 37 million people in the US. It is considered a systemic illness, not just a headache. Recent research has demonstrated that changes may begin to occur in the brain as long as 24 hours before migraine symptoms begin. Many patients have a severe throbbing headache, often on only one side of the head. Some people are nauseated with vomiting. Many are light sensitive (photophobic) and sound sensitive (phonophobic), and these symptoms can persist after the pain goes away. There are a variety of migraine subtypes with symptoms that include weakness, numbness, visual c...
Source: Harvard Health Blog - March 5, 2018 Category: Consumer Health News Authors: Carolyn A. Bernstein, MD, FAHS Tags: Drugs and Supplements Headache Health Migraines Pain Management Source Type: blogs

Migraines, plantar fasciitis, joint pain, heartburn . . . gone
Elizabeth shared her emerging experience of health and life transformation by adopting the Wheat Belly lifestyle: “I am 34 years old, married with no kids. I suffered from hypertension, heart problems, plantar fasciitis, joint pains, heartburn, migraines and I was overweight. “After 60 days of wheat-free lifestyle, I feel so much better. I look better and I have never been so active! So far, I have shed 15 lbs, went down two dress sizes and lost 3 inches around my waist. I might have to do some shopping for smaller clothes! “More importantly, I feel lighter, I can walk miles and climb steps without pain. ...
Source: Wheat Belly Blog - October 18, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Success Stories gluten grains heartburn hypertension joint pain migraine plantar fasciitis Source Type: blogs

Migraines During Pregnancy Can Increase Risks To Mother, Baby
BOSTON (CBS) – Many women of reproductive age suffer from migraines, but a new study out of Denmark finds that having these painful headaches during pregnancy may put the mother and the baby at risk. Danish researchers studied more than more than 200,000 pregnancies and found that women who had migraines during their pregnancies were at higher risk of pregnancy-related hypertension and preeclampsia and that their babies were at a higher risk of complications like low birth weight, preterm birth, respiratory problems and seizures. The hope is that treatment of migraines during pregnancy may reduce these risks to mother and child.
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 9, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Migraines Pregnancy Source Type: news

Migraines linked to increased heart disease risk in women
Conclusion This study shows a strong link between migraine and cardiovascular disease, extending the link already found between migraine and stroke. However, many questions remain. We don't know if the results are relevant to men who have migraines, as all the people in the study were women. We also don't know if the results apply to non-white populations, as most of the women in the study were white. Previous studies on stroke have shown that the group at highest risk is who get an "aura" before a migraine – sensation(s) that tells them the migraine is on its way. But this study did not ask people about aura...
Source: NHS News Feed - June 1, 2016 Category: Consumer Health News Tags: Heart/lungs Neurology Source Type: news

Migraine and menopause - a narrative review
Discussion and conclusion: Many women are informed that their migraines will disappear postmenopause; there are some data to support this, but a specific time frame has not been evidenced. Stroke risk in women with migraine with aura is small in absolute terms, but important at the population level, because migraine is so prevalent. The risk becomes clinically important in the context of additional stroke risk factors, which increase with aging such as hypertension. Estrogen in combined hormonal contraception increases the risk of an ischemic stroke, however, the lower amount of estrogen in HT may not contribute to a m...
Source: Menopause - January 1, 2021 Category: OBGYN Tags: Review Articles Source Type: research

Genetics of migraine
Rev Neurol (Paris). 2021 Jul 22:S0035-3787(21)00603-2. doi: 10.1016/j.neurol.2021.06.002. Online ahead of print.ABSTRACTMigraine is a complex brain disorder explained by the interaction of genetic and environmental factors. In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary small-vessel disorders, the identified genes encode proteins expressed in neurons, astrocytes or vessels, which all increase the susceptibility to cortical spreading depression. Study of monogenic migraines showed that the neurovascular unit plays a prominent role in migraine. Genome-wide ass...
Source: Revue Neurologique - July 26, 2021 Category: Neurology Authors: A Ducros Source Type: research

Women With Migraines Are More Prone To This Scary Health Condition
This study provides really good quality evidence that migraine in women is a risk factor for cardiovascular disease," said Dr. Rebecca Burch, an instructor in the department of neurology at Harvard Medical School in Boston, who wrote an editorial accompanying the study, but was not involved in the research. Migraines have a fairly small effect on cardiovascular risk compared with other known risk factors that have a much larger influence on heart disease, such as smoking, high blood pressure or high cholesterol, Burch said. However, because migraines are relatively common, affecting an estimated 1 in 4 American women, this...
Source: Healthy Living - The Huffington Post - June 2, 2016 Category: Consumer Health News Source Type: news

Genetics of migraine: where are we now?
AbstractMigraine is a complex brain disorder explained by the interaction of genetic and environmental factors. In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary small-vessel disorders, the identified genes code for proteins expressed in neurons, glial cells, or vessels, all of which increase susceptibility to cortical spreading depression. The study of monogenic migraines has shown that the neurovascular unit plays a prominent role in migraine. Genome-wide association studies have identified numerous susceptibility variants that each result in only a small inc...
Source: The Journal of Headache and Pain - February 20, 2023 Category: Neurology Source Type: research

Review of Migraine Incidence and Management in Obstetrics and Gynaecology
ConclusionMigraines have a high incidence in gynaecology and obstetrics. Health care providers must include screening questions when history taking to identify women with migraines and effectively manage them. Proper follow-up and treatment is required for all women with migraines in order to minimize the risk of cerebrovascular events, and negative pregnancy outcomes. Women with migraines are advised to avoid combined hormonal contraception and use progesterone only pills.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - July 18, 2019 Category: OBGYN Source Type: research

Strong Association Between Migraine and Transient Global Amnesia: A National Inpatient Sample Analysis.
Authors: Yi M, Sherzai AZ, Ani C, Shavlik D, Ghamsary M, Lazar E, Sherzai D Abstract The purpose of this article was to explore sex- and race-specific variables and comorbidities associated with transient global amnesia (TGA) using a nationally representative database. Data were obtained from the Nationwide Inpatient Sample using ICD-9 and procedure codes. Descriptive and survey logistic regression analyses were conducted and adjusted for influence of comorbidities, demographic characteristics, and hospitalization-related factors. Patients with migraines were 5.98 times more likely to also have a diagnosis of TGA c...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 13, 2018 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Migraine Headaches in Patients with Upper Extremity Compressive Neuropathy
CONCLUSION: Patients who undergo median and multiple nerve decompression are more likely to suffer from migraine headache. It is important to recognize this overlap and provide comprehensive patient screening for both conditions. This shared predisposition and better understanding of a common disease mechanism and genetics, may provide greater insight into the pathogenesis, and therefore treatment of these clinical problems.PMID:36161789 | DOI:10.1097/PRS.0000000000009684
Source: Hand Surgery - September 26, 2022 Category: Surgery Authors: Lisa Gfrerer Jonathan Lans Christian Chartier Eric Wenzinger William G Austen Kyle R Eberlin Source Type: research

Increased risk of neurodegenerative dementia in women with migraines: A nested case–control study using a national sample cohort
The present study aimed to evaluate the association between migraines and dementia. Data were collected from 11,438 dementia participants who were 1:4 matched by age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia with 45,752 controls from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Dementia was diagnosed using the International Classification of Disease-10 (ICD-10) codes (G30 or F00). For the integrity of diagnoses, we included only participants ≥60 years old who had been diagnosed with an ICD-10 code twice or more during ambulatory visits for the s...
Source: Medicine - February 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research